Modeling blood–brain barrier pathology in cerebrovascular disease in vitro: current and future paradigms

Modeling blood–brain barrier pathology in cerebrovascular disease in vitro: current and future paradigms

Abstract The complexity of the blood–brain barrier (BBB) and neurovascular unit (NVU) was and still is a challenge to bridge. A highly selective, restrictive and dynamic barrier, formed at the interface of blood and brain, the BBB is a “gatekeeper” and guardian of brain homeostasis and it also acts...

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Bibliographic Details
Main Authors: Anuska V. Andjelkovic, Svetlana M. Stamatovic, Chelsea M. Phillips, Gabriela Martinez-Revollar, Richard F. Keep
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Fluids and Barriers of the CNS
Subjects:
Stroke
In vitro models
Neurovascular units
Blood–brain barrier
Vascular dementia
Brain vascular malformation
Online Access:http://link.springer.com/article/10.1186/s12987-020-00202-7

Internet

http://link.springer.com/article/10.1186/s12987-020-00202-7

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