Upstream ORFs Influence Translation Efficiency in the Parasite Trypanosoma cruzi

It is generally accepted that the presence of ORFs in the 5′ untranslated region of eukaryotic transcripts modulates the production of proteins by controlling the translation initiation rate of the main CDS. In trypanosomatid parasites, which almost exclusively depend on post-transcriptional mechani...

Full description

Bibliographic Details
Main Authors: Santiago Radío, Beatriz Garat, José Sotelo-Silveira, Pablo Smircich
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00166/full