Suppression of DLBCL Progression by the E3 Ligase Trim35 Is Mediated by CLOCK Degradation and NK Cell Infiltration

The majority of diffuse large B-cell lymphoma (DLBCL) patients develop relapsed or refractory disease after standard ruxolitinib, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) chemotherapy, which is partly related to a dysregulated tumor immune microenvironment. However, how th...

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Bibliographic Details
Main Authors: Xiyan Tan, Fuyang Cao, Feiyu Tang, Can Lu, Qiaoyan Yu, Songshan Feng, Zhanghuan Yang, Songming Chen, Xiang He, Jiang He, Liang Weng, Lunquan Sun
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2021/9995869