Extracellular Vesicle miR-200c Enhances Gefitinib Sensitivity in Heterogeneous EGFR-Mutant NSCLC

Extracellular Vesicle miR-200c Enhances Gefitinib Sensitivity in Heterogeneous EGFR-Mutant NSCLC

Intratumoral heterogeneity in epidermal growth factor receptor (EGFR)-mutant mutant non-small-cell lung cancer (NSCLC) explains the mixed responses to EGFR-tyrosine kinase inhibitors (TKIs). However, some studies showed tumors with low abundances of EGFR mutation still respond to EGFR-TKI, and the m...

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Bibliographic Details
Main Authors: Chien-Chung Lin, Chin-You Wu, Joseph T. Tseng, Chun-Hua Hung, Shang-Yin Wu, Yu-Ting Huang, Wei-Yuan Chang, Po-Lan Su, Wu-Chou Su
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Biomedicines
Subjects:
extracellular vesicles
miRNA
EGFR mutation
heterogenous
NSCLC
EGFR-TKI
Online Access:https://www.mdpi.com/2227-9059/9/3/243

Internet

https://www.mdpi.com/2227-9059/9/3/243

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