Novel PEGylated Liposomes Enhance Immunostimulating Activity of isRNA

Novel PEGylated Liposomes Enhance Immunostimulating Activity of isRNA

The performance of cationic liposomes for delivery of therapeutic nucleic acids in vivo can be improved and specifically tailored to certain types of cargo and target cells by incorporation of PEG-containing lipoconjugates in the cationic liposome’s composition. Here, we report on the synt...

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Bibliographic Details
Main Authors: Tatyana Kabilova, Elena Shmendel, Daniil Gladkikh, Nina Morozova, Mikhail Maslov, Elena Chernolovskaya, Valentin Vlassov, Marina Zenkova
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Molecules
Subjects:
cationic liposomes
PEG-containing lipoconjugates
transfection
non-viral delivery system
immunostimulating RNA
biodistribution
Online Access:https://www.mdpi.com/1420-3049/23/12/3101

Internet

https://www.mdpi.com/1420-3049/23/12/3101

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