A subclone of HuH-7 with enhanced intracellular hepatitis C virus production and evasion of virus related-cell cycle arrest.

A subclone of HuH-7 with enhanced intracellular hepatitis C virus production and evasion of virus related-cell cycle arrest.

Hepatitis C virus (HCV) cell culture system with JFH-1 strain and HuH-7 cells enabled us to produce infectious HCV particles in vitro, and such system is useful to explore the anti-HCV compounds and to develop the vaccine against HCV. In the present study, we describe the derivation of a cell line t...

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Bibliographic Details
Main Authors: Asako Murayama, Nao Sugiyama, Seiko Yoshimura, Mitsuko Ishihara-Sugano, Takahiro Masaki, Sulyi Kim, Takaji Wakita, Shunji Mishiro, Takanobu Kato
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3527576?pdf=render

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http://europepmc.org/articles/PMC3527576?pdf=render

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