Correlation of the vancomycin 24-h area under the concentration-time curve (AUC24) and trough serum concentration in children with severe infection: A clinical pharmacokinetic study

Background: Vancomycin is a common drug used in children with severe infection. In adults, at least 15 mg/L of the optimal vancomycin trough concentration (Ctrough) is needed to generate the target 24-h area under the concentration-time curve (AUC24) to the minimum inhibitory concentration (MIC) of...

Full description

Bibliographic Details
Main Authors: Satja Issaranggoon na Ayuthaya, Wasan Katip, Peninnah Oberdorfer, Aroonrut Lucksiri
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:International Journal of Infectious Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971219305090