Axis Patterning by BMPs: Cnidarian Network Reveals Evolutionary Constraints

BMP signaling plays a crucial role in the establishment of the dorso-ventral body axis in bilaterally symmetric animals. However, the topologies of the bone morphogenetic protein (BMP) signaling networks vary drastically in different animal groups, raising questions about the evolutionary constraint...

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Bibliographic Details
Main Authors: Grigory Genikhovich, Patrick Fried, M. Mandela Prünster, Johannes B. Schinko, Anna F. Gilles, David Fredman, Karin Meier, Dagmar Iber, Ulrich Technau
Format: Article
Language:English
Published: Elsevier 2015-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715001813