SWATH-MS for prospective identification of protein blood biomarkers of rtPA-associated intracranial hemorrhage in acute ischemic stroke: a pilot study

Abstract Intravenous recombinant tissue plasminogen activator (rtPA) is, besides mechanical thrombectomy, the highest class evidence based reperfusion treatment of acute ischemic stroke (AIS). The biggest concern of the therapy is symptomatic intracranial hemorrhage (sICH), which occurs in 3–7% of a...

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Bibliographic Details
Main Authors: Bartosz Karaszewski, Anna Gójska-Grymajło, Paulina Czaplewska, Bartosz Jabłoński, Aleksandra E. Lewandowska, Daria Ossowska, Adam Wyszomirski, Marek Hałas, Edyta Szurowska
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-97710-9