Stroke-Induced Modulation of Myeloid-Derived Suppressor Cells (MDSCs) and IL-10-Producing Regulatory Monocytes

Stroke-Induced Modulation of Myeloid-Derived Suppressor Cells (MDSCs) and IL-10-Producing Regulatory Monocytes

Background: Stroke patients are at risk of acquiring secondary infections due to stroke-induced immune suppression (SIIS). Immunosuppressive cells comprise myeloid-derived suppressor cells (MDSCs) and immunosuppressive interleukin 10 (IL-10)-producing monocytes. MDSCs represent a small but heterogen...

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Bibliographic Details
Main Authors: Lennart Achmus, Johanna Ruhnau, Sascha Grothe, Bettina von Sarnowski, Barbara M. Bröker, Alexander Dressel, Juliane Schulze, Antje Vogelgesang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Neurology
Subjects:
MDSC (myeloid-derived suppressor cell)
IL10
ischemic stroke
experimental stroke
immune suppression
regulatory monocytes
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2020.577971/full

Internet

https://www.frontiersin.org/articles/10.3389/fneur.2020.577971/full

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