Paradoxical Role of AT-rich Interactive Domain 1A in Restraining Pancreatic Carcinogenesis

Paradoxical Role of AT-rich Interactive Domain 1A in Restraining Pancreatic Carcinogenesis

<i>Background & Aims</i>: ARID1A is postulated to be a tumor suppressor gene owing to loss-of-function mutations in human pancreatic ductal adenocarcinomas (PDAC). However, its role in pancreatic pathogenesis is not clear despite recent studies using genetically engineered mouse (GEM...

Full description

Bibliographic Details
Main Authors: Sammy Ferri-Borgogno, Sugata Barui, Amberly M. McGee, Tamara Griffiths, Pankaj K. Singh, Cortt G. Piett, Bidyut Ghosh, Sanchari Bhattacharyya, Aatur Singhi, Kith Pradhan, Amit Verma, Zac Nagel, Anirban Maitra, Sonal Gupta
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cancers
Subjects:
SWI/SNF
pancreatic cancer
DNA repair
mouse model
Online Access:https://www.mdpi.com/2072-6694/12/9/2695

Internet

https://www.mdpi.com/2072-6694/12/9/2695

Similar Items