Cytotoxic granule secretion by lymphocytes and its link to immune homeostasis [version 1; referees: 2 approved]

The granule-dependent cytotoxic activity of T and natural killer lymphocytes has progressively emerged as an important effector pathway not only for host defence but also for immune regulation. The analysis of an early-onset, severe, primary immune dysregulatory syndrome known as hemophagocytic lymp...

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Bibliographic Details
Main Authors: Geneviève de Saint Basile, Fernando E. Sepulveda, Sophia Maschalidi, Alain Fischer
Format: Article
Language:English
Published: F1000 Research Ltd 2015-09-01
Series:F1000Research
Subjects:
Online Access:http://f1000research.com/articles/4-930/v1