Chaperone-Based Therapies for Disease Modification in Parkinson’s Disease

Parkinson’s disease (PD) is the second most common neurodegenerative disorder and is characterized by the presence of pathological intracellular aggregates primarily composed of misfolded α-synuclein. This pathology implicates the molecular machinery responsible for maintaining protein homeostasis (...

Full description

Bibliographic Details
Main Authors: Erik L. Friesen, Mitch L. De Snoo, Luckshi Rajendran, Lorraine V. Kalia, Suneil K. Kalia
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Parkinson's Disease
Online Access:http://dx.doi.org/10.1155/2017/5015307