Monoclonal antibodies specific for the hemagglutinin-neuraminidase protein define neutralizing epitopes specific for Newcastle disease virus genotype 2.VII from Egypt

Monoclonal antibodies specific for the hemagglutinin-neuraminidase protein define neutralizing epitopes specific for Newcastle disease virus genotype 2.VII from Egypt

Abstract Background Newcastle disease is a devastating disease in poultry caused by virulent Newcastle disease virus (NDV), a paramyxovirus endemic in many regions of the world despite intensive vaccination. Phylogenetic analyses reveal ongoing evolution of the predominant circulating genotype 2.VII...

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Bibliographic Details
Main Authors: Ibrahim Moharam, Olayinka Asala, Sven Reiche, Hafez Hafez, Martin Beer, Timm Harder, Christian Grund
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Virology Journal
Subjects:
Monoclonal antibody
Newcastle disease virus
Genotype 2.VII
Antigenicity
Hemagglutinin-Neuraminidase protein
Conformational epitopes
Online Access:https://doi.org/10.1186/s12985-021-01540-0

Internet

https://doi.org/10.1186/s12985-021-01540-0

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