Synthesis, characterization and evaluation of transfection efficiency of dexamethasone conjugated poly(propyleneimine) nanocarriers for gene delivery#

Synthesis, characterization and evaluation of transfection efficiency of dexamethasone conjugated poly(propyleneimine) nanocarriers for gene delivery#

Context: Polypropylenimine (PPI), a cationic dendrimer with defined structure and positive surface charge, is a potent non-viral vector. Dexamethasone (Dexa) conveys to the nucleus through interaction with its intracellular receptor. Objective: This study develops efficient and non-toxic gene carrie...

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Bibliographic Details
Main Authors: Bizhan Malaekeh-Nikouei, Mehdi Rezaee, Leila Gholami, Naghmeh Sanjar Mousavi, Reza Kazemi Oskuee
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Pharmaceutical Biology
Subjects:
gene transfer techniques
non-viral vectors
dendrimers
polyplexes
nuclear localization signals
Online Access:http://dx.doi.org/10.1080/13880209.2018.1517183

Internet

http://dx.doi.org/10.1080/13880209.2018.1517183

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