Aberrantly high activation of a FoxM1–STMN1 axis contributes to progression and tumorigenesis in FoxM1-driven cancers

Aberrantly high activation of a FoxM1–STMN1 axis contributes to progression and tumorigenesis in FoxM1-driven cancers

Abstract Fork-head box protein M1 (FoxM1) is a transcriptional factor which plays critical roles in cancer development and progression. However, the general regulatory mechanism of FoxM1 is still limited. STMN1 is a microtubule-binding protein which can inhibit the assembly of microtubule dimer or p...

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Bibliographic Details
Main Authors: Jun Liu, Jipeng Li, Ke Wang, Haiming Liu, Jianyong Sun, Xinhui Zhao, Yanping Yu, Yihuan Qiao, Ye Wu, Xiaofang Zhang, Rui Zhang, Angang Yang
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-020-00396-0

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https://doi.org/10.1038/s41392-020-00396-0

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