Group II Metabotropic Glutamate Receptors: Role in Pain Mechanisms and Pain Modulation

Group II Metabotropic Glutamate Receptors: Role in Pain Mechanisms and Pain Modulation

Glutamate is the main excitatory neurotransmitter in the nervous system and plays a critical role in nociceptive processing and pain modulation. G-protein coupled metabotropic glutamate receptors (mGluRs) are widely expressed in the central and peripheral nervous system, and they mediate neuronal ex...

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Bibliographic Details
Main Authors: Mariacristina Mazzitelli, Enza Palazzo, Sabatino Maione, Volker Neugebauer
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Molecular Neuroscience
Subjects:
glutamate
pain
nociception
metabotropic glutamate receptor
mGluR
analgesia
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2018.00383/full

Internet

https://www.frontiersin.org/article/10.3389/fnmol.2018.00383/full

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