CD24-targeted intraoperative fluorescence image-guided surgery leads to improved cytoreduction of ovarian cancer in a preclinical orthotopic surgical model

CD24-targeted intraoperative fluorescence image-guided surgery leads to improved cytoreduction of ovarian cancer in a preclinical orthotopic surgical model

Background: The completeness of resection is a key prognostic indicator in patients with ovarian cancer, and the application of tumour-targeted fluorescence image-guided surgery (FIGS) has led to improved detection of peritoneal metastases during cytoreductive surgery. CD24 is highly expressed in ov...

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Bibliographic Details
Main Authors: Katrin Kleinmanns, Vibeke Fosse, Ben Davidson, Elvira García de Jalón, Olav Tenstad, Line Bjørge, Emmet McCormack
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:EBioMedicine
Subjects:
Intraoperative imaging
Biomarker
Debulking surgery
Near-infrared fluorescence
HGSOC
Patient-derived xenograft
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420301584

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http://www.sciencedirect.com/science/article/pii/S2352396420301584

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