Soluble Recombinant Hemagglutinin Protein of H1N1pdm09 Influenza Virus Elicits Cross-Protection Against a Lethal H5N1 Challenge in Mice

Soluble Recombinant Hemagglutinin Protein of H1N1pdm09 Influenza Virus Elicits Cross-Protection Against a Lethal H5N1 Challenge in Mice

Currently, influenza vaccines are produced using embryonated chicken eggs. Recently, recombinant influenza vaccines have been developed as a potential alternative to egg-grown vaccines. In this study, we evaluated the efficacy of soluble recombinant hemagglutinin (HA) protein produced in human cell...

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Bibliographic Details
Main Authors: Shinya Yamada, Atsuhiro Yasuhara, Yoshihiro Kawaoka
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Microbiology
Subjects:
influenza
vaccines
recombinant hemagglutinin protein
intramuscular immunization
cross-protection
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02031/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.02031/full

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