SNP-SNP interactions discovered by logic regression explain Crohn's disease genetics.

In genome-wide association studies (GWAS), the association between each single nucleotide polymorphism (SNP) and a phenotype is assessed statistically. To further explore genetic associations in GWAS, we considered two specific forms of biologically plausible SNP-SNP interactions, 'SNP intersec...

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Bibliographic Details
Main Authors: Irina Dinu, Surakameth Mahasirimongkol, Qi Liu, Hideki Yanai, Noha Sharaf Eldin, Erin Kreiter, Xuan Wu, Shahab Jabbari, Katsushi Tokunaga, Yutaka Yasui
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3470545?pdf=render