HGF/c-met/Stat3 signaling during skin tumor cell invasion: indications for a positive feedback loop

<p>Abstract</p> <p>Background</p> <p>Stat3 is a cytokine- and growth factor-inducible transcription factor that regulates cell motility, migration, and invasion under normal and pathological situations, making it a promising target for cancer therapeutics. The hepatocyt...

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Bibliographic Details
Main Authors: Shi Runhua, Gill Jennifer N, Hughes Kendall, Yin Weihong, Syed Zanobia A, Clifford John L
Format: Article
Language:English
Published: BMC 2011-05-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/11/180