Cholesterol as an Endogenous ERRα Agonist: A New Perspective to Cancer Treatment

Cholesterol as an Endogenous ERRα Agonist: A New Perspective to Cancer Treatment

The estrogen-related receptors (ERRs) are important members of nuclear receptors which contain three isoforms (α, β, and γ). ERRα is the best-characterized isoform expressed mainly in high-energy demanding tissues where it preferentially works in association with the peroxisome proliferator-activate...

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Bibliographic Details
Main Authors: Ivan Casaburi, Adele Chimento, Arianna De Luca, Marta Nocito, Sara Sculco, Paola Avena, Francesca Trotta, Vittoria Rago, Rosa Sirianni, Vincenzo Pezzi
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Endocrinology
Subjects:
ERRα
cholesterol
cancer metabolism
breast and prostate cancer
colonrectal cancer
adrenocortical carcinoma (ACC)
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2018.00525/full

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https://www.frontiersin.org/article/10.3389/fendo.2018.00525/full

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