Replication stress-induced Exo1 phosphorylation is mediated by Rad53/Pph3 and Exo1 nuclear localization is controlled by 14-3-3 proteins

Replication stress-induced Exo1 phosphorylation is mediated by Rad53/Pph3 and Exo1 nuclear localization is controlled by 14-3-3 proteins

Abstract Background Mechanisms controlling DNA resection at sites of damage and affecting genome stability have been the subject of deep investigation, though their complexity is not yet fully understood. Specifically, the regulatory role of post-translational modifications in the localization, stab...

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Bibliographic Details
Main Authors: Nagaraja Chappidi, Giuseppe De Gregorio, Stefano Ferrari
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Cell Division
Subjects:
14-3-3
Budding yeast
DNA replication
Exonuclease-1
Phosphorylation
Pph3
Online Access:http://link.springer.com/article/10.1186/s13008-018-0044-2

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http://link.springer.com/article/10.1186/s13008-018-0044-2

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