Genome-wide association study of phenotypes measuring progression from first cocaine or opioid use to dependence reveals novel risk genes

Genome-wide association study of phenotypes measuring progression from first cocaine or opioid use to dependence reveals novel risk genes

Aim: Substance use disorders (SUD) result in substantial morbidity and mortality worldwide. Opioids, and to a lesser extent cocaine, contribute to a large percentage of this health burden. Despite their high heritability, few genetic risk loci have been identified for either opioid or cocaine depend...

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Bibliographic Details
Main Authors: Richard Sherva, Congcong Zhu, Leah Wetherill, Howard J. Edenberg, Emma Johnson, Louisa Degenhardt, Arpana Agrawal, Nicholas G. Martin, Elliot Nelson, Henry R. Kranzler, Joel Gelernter, Lindsay A. Farrer
Format: Article
Language:English
Published: Open Exploration Publishing Inc. 2021-02-01
Series:Exploration of Medicine
Subjects:
substance use disorders
cocaine use disorders
opioid use disorders
genetics
fam78b
gwas
Online Access:https://www.explorationpub.com/Journals/em/Article/100132

Internet

https://www.explorationpub.com/Journals/em/Article/100132

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