Deep Brain Stimulation and L-DOPA Therapy: Concepts of Action and Clinical Applications in Parkinson's Disease

L-DOPA is still the most effective pharmacological therapy for the treatment of motor symptoms in Parkinson's disease (PD) almost four decades after it was first used. Deep brain stimulation (DBS) is a safe and highly effective treatment option in patients with PD. Even though a clear understan...

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Bibliographic Details
Main Authors: Muthuraman Muthuraman, Nabin Koirala, Dumitru Ciolac, Bogdan Pintea, Martin Glaser, Stanislav Groppa, Gertrúd Tamás, Sergiu Groppa
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Neurology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2018.00711/full