Activation of cGAS/STING pathway upon paramyxovirus infection

Activation of cGAS/STING pathway upon paramyxovirus infection

Summary: During inflammatory diseases, cancer, and infection, the cGAS/STING pathway is known to recognize foreign or self-DNA in the cytosol and activate an innate immune response. Here, we report that negative-strand RNA paramyxoviruses, Nipah virus (NiV), and measles virus (MeV), can also trigger...

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Bibliographic Details
Main Authors: Mathieu Iampietro, Claire Dumont, Cyrille Mathieu, Julia Spanier, Jonathan Robert, Aude Charpenay, Sébastien Dupichaud, Kévin P. Dhondt, Noémie Aurine, Rodolphe Pelissier, Marion Ferren, Stéphane Mély, Denis Gerlier, Ulrich Kalinke, Branka Horvat
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:iScience
Subjects:
immune system
molecular biology
Virology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221004879

Internet

http://www.sciencedirect.com/science/article/pii/S2589004221004879

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