Differential mRNA Expression Levels of Human Histone-Modifying Enzymes in Normal Karyotype B Cell Pediatric Acute Lymphoblastic Leukemia

Differential mRNA Expression Levels of Human Histone-Modifying Enzymes in Normal Karyotype B Cell Pediatric Acute Lymphoblastic Leukemia

Histone modification enzymes regulate gene expression by altering the accessibility of promoters to transcription factors. We sought to determine whether the genes encoding histone modification enzymes are dysregulated in pediatric acute lymphoblastic leukemia (ALL). A real-time PCR array was design...

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Bibliographic Details
Main Authors: Jian Ni, Na Wang, Dong Wu, Jian Wang, Xing Feng, Wen-Li Zhao, Lan Cao, Jun Lu, Shao-Yan Hu, Li-Chao Sun, Xiao-Juan Du, Li Pang, Yan-Fang Tao, Jian Pan
Format: Article
Language:English
Published: MDPI AG 2013-02-01
Series:International Journal of Molecular Sciences
Subjects:
histone-modifying enzymes
pediatric acute lymphoblastic leukemia
real-time PCR array
Online Access:http://www.mdpi.com/1422-0067/14/2/3376

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http://www.mdpi.com/1422-0067/14/2/3376

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