Bee venom phospholipase A2 ameliorates amyloidogenesis and neuroinflammation through inhibition of signal transducer and activator of transcription-3 pathway in Tg2576 mice

Bee venom phospholipase A2 ameliorates amyloidogenesis and neuroinflammation through inhibition of signal transducer and activator of transcription-3 pathway in Tg2576 mice

Abstract Background Neuroinflammation and accumulation of β-amyloid (Aβ) play a significant role in the onset and progression of Alzheimer’s disease (AD). Our previous study demonstrated that signal transducer and activator of transcription-3 (STAT3) plays a major role in neuroinflammation and amylo...

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Bibliographic Details
Main Authors: Hyeon Joo Ham, Sang-Bae Han, Jaesuk Yun, In Jun Yeo, Young Wan Ham, Se Hyun Kim, Pil-Hoon Park, Dong-Young Choi, Jin Tae Hong
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Translational Neurodegeneration
Subjects:
Bee venom phospholipase A2
Alzheimer’s disease
Amyloidogenesis
Neuroinflammation
STAT3
Online Access:http://link.springer.com/article/10.1186/s40035-019-0167-7

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http://link.springer.com/article/10.1186/s40035-019-0167-7

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