Cyclooxygenase-2 enhances α2β1 integrin expression and cell migration via EP1 dependent signaling pathway in human chondrosarcoma cells

Cyclooxygenase-2 enhances α2β1 integrin expression and cell migration via EP1 dependent signaling pathway in human chondrosarcoma cells

<p>Abstract</p> <p>Background</p> <p>Cyclooxygenase (COX)-2, the inducible isoform of prostaglandin (PG) synthase, has been implicated in tumor metastasis. Interaction of COX-2 with its specific EP receptors on the surface of cancer cells has been reported to induce can...

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Bibliographic Details
Main Authors: Hsu Chin-Jung, Yang Wei-Hung, Chen Hsien-Te, Huang Chun-Yin, Chang Chih-Shiang, Fong Yi-Chin, Liu Ju-Fang, Jeng Long-Bin, Chen Chih-Yi, Tang Chih-Hsin
Format: Article
Language:English
Published: BMC 2010-02-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/43

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http://www.molecular-cancer.com/content/9/1/43

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