Intracellular and Intercellular Mitochondrial Dynamics in Parkinson’s Disease

The appearance of alpha-synuclein-positive inclusion bodies (Lewy bodies) and the loss of catecholaminergic neurons are the primary pathological hallmarks of Parkinson’s disease (PD). However, the dysfunction of mitochondria has long been recognized as a key component in the progression of the disea...

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Bibliographic Details
Main Authors: Dario Valdinocci, Rui F. Simões, Jaromira Kovarova, Teresa Cunha-Oliveira, Jiri Neuzil, Dean L. Pountney
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00930/full