Long Term Glaucoma Drug Delivery Using a Topically Retained Gel/Microsphere Eye Drop

Abstract The purpose of this study was to characterize and determine the efficacy of a long-term, non-invasive gel/microsphere (GMS) eye drop for glaucoma. This novel drug delivery system is comprised of a thermoresponsive hydrogel carrier and drug-loaded polymer microspheres. In vitro release of br...

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Bibliographic Details
Main Authors: Morgan V. Fedorchak, Ian P. Conner, Joel S. Schuman, Anthony Cugini, Steven R. Little
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-09379-8