Tanshinone IIA attenuates renal injury during hypothermic preservation via the MEK/ERK1/2/GSK-3β pathway

Tanshinone IIA attenuates renal injury during hypothermic preservation via the MEK/ERK1/2/GSK-3β pathway

Abstract Background Oxidative stress-induced injury during hypothermic preservation is a universal problem that delays graft function and decrease the success of organ transplantation. Tanshinone IIA (Tan IIA) was reported to exhibit a variety of biochemical activities, including protection against...

Full description

Bibliographic Details
Main Authors: Linhao Xu, Yizhou Xu, Zhoujing Zhu, Huiquan Gu, Chaofeng Chen, Jian Chen
Format: Article
Language:English
Published: BMC 2021-10-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Tanshinone IIA
Hypothermic preservation
Celsior solution
Reactive oxygen species
Apoptosis
Online Access:https://doi.org/10.1186/s12906-021-03427-7

Internet

https://doi.org/10.1186/s12906-021-03427-7

Similar Items