Regulation of PCNA cycling on replicating DNA by RFC and RFC-like complexes

Replication-Factor-C (RFC) and RFC-like complexes (RLCs) mediate chromatin engagement of the proliferating cell nuclear antigen (PCNA). Here authors use biochemical and single molecule measurements to show that ATAD5-RLC has the most potent PCNA unloading activity and forms structurally distinct int...

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Bibliographic Details
Main Authors: Mi-Sun Kang, Eunjin Ryu, Seung-Won Lee, Jieun Park, Na Young Ha, Jae Sun Ra, Yeong Jae Kim, Jinwoo Kim, Mohamed Abdel-Rahman, Su Hyung Park, Kyoo-young Lee, Hajin Kim, Sukhyun Kang, Kyungjae Myung
Format: Article
Language:English
Published: Nature Publishing Group 2019-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-10376-w