Biochemical discrimination between selenium and sulfur 1: a single residue provides selenium specificity to human selenocysteine lyase.

Biochemical discrimination between selenium and sulfur 1: a single residue provides selenium specificity to human selenocysteine lyase.

Selenium and sulfur are two closely related basic elements utilized in nature for a vast array of biochemical reactions. While toxic at higher concentrations, selenium is an essential trace element incorporated into selenoproteins as selenocysteine (Sec), the selenium analogue of cysteine (Cys). Sec...

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Bibliographic Details
Main Authors: Ruairi Collins, Ann-Louise Johansson, Tobias Karlberg, Natalia Markova, Susanne van den Berg, Kenneth Olesen, Martin Hammarström, Alex Flores, Herwig Schüler, Lovisa Holmberg Schiavone, Peter Brzezinski, Elias S J Arnér, Martin Högbom
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3266270?pdf=render

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http://europepmc.org/articles/PMC3266270?pdf=render

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