Improved Placement of Multi-mapping Small RNAs

High-throughput sequencing of small RNAs (sRNA-seq) is a popular method used to discover and annotate microRNAs (miRNAs), endogenous short interfering RNAs (siRNAs), and Piwi-associated RNAs (piRNAs). One of the key steps in sRNA-seq data analysis is alignment to a reference genome. sRNA-seq librari...

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Bibliographic Details
Main Authors: Nathan R. Johnson, Jonathan M. Yeoh, Ceyda Coruh, Michael J. Axtell
Format: Article
Language:English
Published: Oxford University Press 2016-07-01
Series:G3: Genes, Genomes, Genetics
Subjects:
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.116.030452