Hyperhomocysteinemia is key for increased susceptibility to PND in aged mice

Abstract Background Postoperative neurocognitive disorder (PND) is a severe postoperative complication with no effective therapy that affects up to 19–52% of senior patients. Age and surgery type have been identified as risk factors. However, what caused the increased risk in the elderly is poorly u...

Full description

Bibliographic Details
Main Authors: Guangchao Zhao, Jiao Deng, Yuan Shen, Peng Zhang, Hailong Dong, Zhongcong Xie, Lize Xiong
Format: Article
Language:English
Published: Wiley 2019-08-01
Series:Annals of Clinical and Translational Neurology
Online Access:https://doi.org/10.1002/acn3.50838