Mouse Schwann cells activate MHC class I and II restricted T-cell responses, but require external peptide processing for MHC class II presentation

Mouse Schwann cells activate MHC class I and II restricted T-cell responses, but require external peptide processing for MHC class II presentation

Schwann cells are the myelinating glia cells of the peripheral nervous system (PNS). In inflammatory neuropathies like the Guillain-Barré syndrome (GBS) Schwann cells become target of an autoimmune response, but may also modulate local inflammation. Here, we tested the functional relevance of Schwan...

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Bibliographic Details
Main Authors: Gerd Meyer zu Hörste, Holger Heidenreich, Anne K. Mausberg, Helmar C. Lehmann, Anneloor L.M.A. ten Asbroek, José T. Saavedra, Frank Baas, Hans-Peter Hartung, Heinz Wiendl, Bernd C. Kieseier
Format: Article
Language:English
Published: Elsevier 2010-02-01
Series:Neurobiology of Disease
Subjects:
Inflammatory neuropathy
Guillain-Barré syndrome
Antigen presentation
Schwann cell
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996109003283

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http://www.sciencedirect.com/science/article/pii/S0969996109003283

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