The Role of HSP70 in the Protective Effects of NVP-AUY922 on Multiple Organ Dysfunction Syndrome in Endotoxemic Rats

The Role of HSP70 in the Protective Effects of NVP-AUY922 on Multiple Organ Dysfunction Syndrome in Endotoxemic Rats

Sepsis is defined as a life-threatening organ dysfunction syndrome with high morbidity and mortality caused by bacterial infection. The major characteristics of sepsis are systemic inflammatory responses accompanied with elevated oxidative stress, leading to multiple organ dysfunction syndrome (MODS...

Full description

Bibliographic Details
Main Authors: Pang-Yen Liu, Hsin-Hsueh Shen, Ching-Wen Kung, Shu-Ying Chen, Chia-Hsien Lu, Yen-Mei Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Pharmacology
Subjects:
HSP-70
endotoxemia
MODS
septic shock
HSP-90 inhibitor
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.724515/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.724515/full

Similar Items