Chylomicrons promote intestinal absorption and systemic dissemination of dietary antigen (ovalbumin) in mice.

BACKGROUND:A small fraction of dietary protein survives enzymatic degradation and is absorbed in potentially antigenic form. This can trigger inflammatory responses in patients with celiac disease or food allergies, but typically induces systemic immunological tolerance (oral tolerance). At present...

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Bibliographic Details
Main Authors: Yuehui Wang, Sarbani Ghoshal, Martin Ward, Willem de Villiers, Jerold Woodward, Erik Eckhardt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2793525?pdf=render