Transforming growth factor beta 1 induces methylation changes in lung fibroblasts.

Idiopathic pulmonary fibrosis is a complex disease of unknown etiology. Environmental factors can affect disease susceptibility via epigenetic effects. Few studies explore global DNA methylation in lung fibroblasts, but none have focused on transforming growth factor beta-1 (TGF-β1) as a potential m...

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Bibliographic Details
Main Authors: Miguel Negreros, James S Hagood, Celia R Espinoza, Yalbi I Balderas-Martínez, Moisés Selman, Annie Pardo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0223512