Optimizing exchange transfusion for severe unconjugated hyperbilirubinemia: studies in the Gunn rat.

BACKGROUND: Severe unconjugated hyperbilirubinemia carries the risk of neurotoxicity. Phototherapy (PT) and exchange transfusion (ET) are cornerstones in the treatment of unconjugated hyperbilirubinemia. Studies to improve ET efficacy have been hampered by the low application of ET in humans and by...

Full description

Bibliographic Details
Main Authors: Andrea B Schreuder, Jana Vanikova, Libor Vitek, Rick Havinga, Charles E Ahlfors, Christian V Hulzebos, Henkjan J Verkade
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3797100?pdf=render