Cardiosomal microRNAs Are Essential in Post-Infarction Myofibroblast Phenoconversion

Cardiosomal microRNAs Are Essential in Post-Infarction Myofibroblast Phenoconversion

The inclusion of microRNAs (miRNAs) in extracellular microvesicles/exosomes (named cardiosomes when deriving from cardiomyocytes) allows their active transportation and ensures cell-cell communication. We hypothesize that cardiosomal miRNAs play a pivotal role in the activation of myofibroblasts fol...

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Bibliographic Details
Main Authors: Marco B. Morelli, Jun Shu, Celestino Sardu, Alessandro Matarese, Gaetano Santulli
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:International Journal of Molecular Sciences
Subjects:
cardiac ischemia
epigenetics
exosomes
extracellular vesicles
fibroblasts
inflammation
microrna
myocardial infarction
myofibroblast activation
Online Access:https://www.mdpi.com/1422-0067/21/1/201

Internet

https://www.mdpi.com/1422-0067/21/1/201

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