Development of polycationic amphiphilic cyclodextrin nanoparticles for anticancer drug delivery

Background: Paclitaxel is a potent anticancer drug that is effective against a wide spectrum of cancers. To overcome its bioavailability problems arising from very poor aqueous solubility and tendency to recrystallize upon dilution, paclitaxel is commercially formulated with co-solvents such as Crem...

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Bibliographic Details
Main Authors: Gamze Varan, Juan M. Benito, Carmen Ortiz Mellet, Erem Bilensoy
Format: Article
Published: Beilstein-Institut 2017-07-01
Series:Beilstein Journal of Nanotechnology
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