CALR-TLR4 Complex Inhibits Non-Small Cell Lung Cancer Progression by Regulating the Migration and Maturation of Dendritic Cells

BackgroundLung cancer is a common malignant tumor that threatens human life and is associated with high morbidity and mortality rates. Calreticulin (CALR) is a antigen characteristic of immunogenic cell death in non-small cell lung cancer (NSCLC), which is closely related to anti-tumor immunity, but...

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Bibliographic Details
Main Authors: Ruo Chen, Min Huang, Xu Yang, Xiao-Hong Chen, Ming-Yan Shi, Zhuo-Fan Li, Zhi-Nan Chen, Ke Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Oncology
Subjects:
DCs
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.743050/full