Platelet-Rich Plasma Modulates Gap Junction Functionality and Connexin 43 and 26 Expression During TGF-β1–Induced Fibroblast to Myofibroblast Transition: Clues for Counteracting Fibrosis

Platelet-Rich Plasma Modulates Gap Junction Functionality and Connexin 43 and 26 Expression During TGF-β1–Induced Fibroblast to Myofibroblast Transition: Clues for Counteracting Fibrosis

Skeletal muscle repair/regeneration may benefit by Platelet-Rich Plasma (PRP) treatment owing to PRP pro-myogenic and anti-fibrotic effects. However, PRP anti-fibrotic action remains controversial. Here, we extended our previous researches on the inhibitory effects of PRP on in vitro transforming gr...

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Bibliographic Details
Main Authors: Roberta Squecco, Flaminia Chellini, Eglantina Idrizaj, Alessia Tani, Rachele Garella, Sofia Pancani, Paola Pavan, Franco Bambi, Sandra Zecchi-Orlandini, Chiara Sassoli
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cells
Subjects:
α-smooth muscle actin
confocal microscopy
connexin 43
connexin 26
fibrosis
gap junctions
Online Access:https://www.mdpi.com/2073-4409/9/5/1199

Internet

https://www.mdpi.com/2073-4409/9/5/1199

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