Stiffness dependent separation of cells in a microfluidic device.

Abnormal cell mechanical stiffness can point to the development of various diseases including cancers and infections. We report a new microfluidic technique for continuous cell separation utilizing variation in cell stiffness. We use a microfluidic channel decorated by periodic diagonal ridges that...

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Bibliographic Details
Main Authors: Gonghao Wang, Wenbin Mao, Rebecca Byler, Krishna Patel, Caitlin Henegar, Alexander Alexeev, Todd Sulchek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24146787/pdf/?tool=EBI