Single dose testosterone increases total cholesterol levels and induces the expression of HMG CoA Reductase

<p>Abstract</p> <p>Background</p> <p>Cholesterol is mainly synthesised in liver and the rate-limiting step is the reduction of 3-hydroxy-3methylglutaryl coenzyme A (HMG-CoA) to mevalonate, a reaction catalysed by HMG-CoA reductase (HMGCR). There is a comprehensive body...

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Bibliographic Details
Main Authors: Gårevik Nina, Skogastierna Cristine, Rane Anders, Ekström Lena
Format: Article
Language:English
Published: BMC 2012-03-01
Series:Substance Abuse Treatment, Prevention, and Policy
Subjects:
Online Access:http://www.substanceabusepolicy.com/content/7/1/12