Altered signal pathway in granulocytes from patients with hypercholesterolemia

Altered signal pathway in granulocytes from patients with hypercholesterolemia

In the present study the signal transduction of the formyl-Met-Leu-Phe receptor was studied in granulocytes obtained from control subjects and patients with elevated low density lipoprotein levels. According to our results, 10 nm formyl-Met-Leu-Phe in control cells activates phospholipase C inducing...

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Bibliographic Details
Main Authors: György Paragh, Éva Kovács, Ildikó Seres, Tamás Keresztes, Zoltán Balogh, Jenõ Szabó, Farkas Teichmann, Gabriella Fóris
Format: Article
Language:English
Published: Elsevier 1999-09-01
Series:Journal of Lipid Research
Subjects:
hypercholesterolemia
granulocytes
formyl-Met-Leu-Phe
Ca2+ signal
inositol phosphates
leukotrienes
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520334209

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http://www.sciencedirect.com/science/article/pii/S0022227520334209

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