Mepivacaine reduces calcium transients in isolated murine ventricular cardiomyocytes

Abstract Background The potential mechanism of mepivacaine’s myocardial depressant effect observed in papillary muscle has not yet been investigated at cellular level. Therefore, we evaluated mepivacaine’s effects on Ca2+ transient in isolated adult mouse cardiomyocytes. Methods Single ventricular m...

Full description

Bibliographic Details
Main Authors: Matias Mosqueira, Güçlü Aykut, Rainer H. A. Fink
Format: Article
Language:English
Published: BMC 2020-01-01
Series:BMC Anesthesiology
Subjects:
Online Access:https://doi.org/10.1186/s12871-019-0926-0