CCR5 as a Natural and Modulated Target for Inhibition of HIV

Human immunodeficiency virus type 1 (HIV-1) infection of target cells requires CD4 and a co-receptor, predominantly the chemokine receptor CCR5. CCR5-delta32 homozygosity results in a truncated protein providing natural protection against HIV infection—this without detrimental effects to the host—a...

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Bibliographic Details
Main Authors: Bryan P. Burke, Maureen P. Boyd, Helen Impey, Louis R. Breton, Jeffrey S. Bartlett, Geoff P. Symonds, Gero Hütter
Format: Article
Language:English
Published: MDPI AG 2013-12-01
Series:Viruses
Subjects:
C46
HIV
Online Access:http://www.mdpi.com/1999-4915/6/1/54